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Typhoid Fever Causes, Symptoms, Treatment and Vaccine

TYPHOID FEVER

⁃ This is the severe infectious disease marked by fever and septicemia.
⁃ It is very common fever in some areas. mostly among travellers.
⁃ An estimated 20 million cases of typhoid fever and 24,0000 deaths occur in all over the world.
⁃ Some in endemic  areas where the sanitation system is poor.
⁃ CAUSES:-
⁃ It is caused by the S.typhi.
⁃ gram negative bacteria that enter the gastrointestinal tract.
⁃ Infention in the billary tract.
⁃ It is most commonly transmitted by the fecal-oral route through water or food contaminated by humsn feces.
⁃ Lymtyphoid tissues and walls of the ileum and colon seeding thrvintestinal tract with millions of bacilli.
⁃ SYMPTOMS:-
⁃ most common symptoms of gastrointestinal symptoms may develop within 1 hour of salmonella., typhi ingestion.
⁃ Fever, malaise.
⁃ Anorexia , myalgia, headache and slow pulse  rate.
⁃ Fleeting rash.
⁃ Chills and diapherosis increasing abdominal pain and digestion.
⁃ Diarrhoea or constipation
⁃ Abdominal pain
⁃ Weakness and exhaution.
⁃ Cough and moist crackles.
⁃ Bacteria spread through the blood stream.
⁃ Fatigue and ilness increasing.
⁃ Some time internal bleeding usually develops as the result of gastrointestinsl ulcers.
⁃ Abscesses and intestinal perforation as result hypovemic shock may aoccur.
⁃ Damage te the liver and spleen .
⁃ Most serious complications of causing typhoid fever are pneumonia , thrombophlebitis, osteomyelitis, septic arthritis .

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