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Parkinson's disease - Symptoms and causes

PARKINSONS DISEASE

this is the common  chronic degenerative disease of the central nervous system that produces progressive movement disorders and changed in congition and mood.
A pill-polling tremor of hands , muscular rigidity, loss of facial expression, difficulty initiating mocements such as, akinesia, bradykinesia and gait disturbances .
This disease is mostly found in the people who are over the age of 68.
CAUSES:-
Dopamine production by brain cells in the substantia nigra is dimminished in the the disease.
Clusters in families are often.
Genetics conditions
Viruses, toxins or drugs.
SYMPTOMS:-
Tremors in one or more extemties when the hand at its rest.
Fatigue , malaise.
During sleep decreased Anxiety or stress  .
Change in the vocal quality
Shuffling gait that becomes faster after a few steps.
TREATMENT:-
Maintain the function for ad long as possible and relieve symptoms.
Administer medications such as,selegine, levodopa/carbidopa:- dopamine agonists .
Inhibitors of catechol-o-methyltranseferase .
Monoamine oxidase-B inhibitors.
Surgical therapy , in which may involve transplantation of dopamine-secreting cells into affected areas of brain or insertion of electricsl brain stimulators into thr subthalamic nucleus .
Phsyical therapy is given helping to maintain muscle tone and function.

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